Currently browsing: “T-cell mediated immunity”

Immunity on Dendritic Cells Potentiates Th17-Mediated Stimulation of Dopamine Receptor D5 Expressed

KEYWORDS: 2012 • CD4+ • DC maturation • Dendritic cells • LPS-induced • neurotransmitters • Rodrigo Pacheco • T-cell mediated immunity • Th17 phenotype

ABSTRACT: Dendritic cells (DCs) are responsible for priming T cells and for promoting their differentiation from naive T cells into appropriate effector cells. Emerging evidence suggests that neurotransmitters can modulate T cell-mediated immunity. However, the involvement of specific neurotransmitters or receptors remains poorly understood. In this study, we analyzed the role of dopamine in the regulation of DC […]

Role of dopamine in the physiology of T-cells and dendritic cells

KEYWORDS: CD8+ cytotoxic • Dendritic cells • Sebastián Bernales • T-cell mediated immunity • T-cells CD4+ helper • T-cells Dopamine

Dendritic cells (DCs) are responsible for priming T-cells and for promoting their differentiation from naïve T-cells into appropriate effector cells. Because of their fundamental roles in controlling immunity, DCs and T-cells require tight regulatory mechanisms. Several studies have shown that dopamine, not only mediate interactions into the nervous system, but can also contribute to the […]