Currently browsing: “T-cell mediated immunity”

Immunity on Dendritic Cells Potentiates Th17-Mediated Stimulation of Dopamine Receptor D5 Expressed

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ABSTRACT: Dendritic cells (DCs) are responsible for priming T cells and for promoting their differentiation from naive T cells into appropriate effector cells. Emerging evidence suggests that neurotransmitters can modulate T cell-mediated immunity. However, the involvement of specific neurotransmitters or receptors remains poorly understood. In this study, we analyzed the role of dopamine in the regulation of DC […]

Prado C., Contreras F., González H., Díaz P., Elgueta D., Barrientos M., Herrada A. A., Lladser À., Bernales S. and Pacheco R. Immunity on Dendritic Cells Potentiates Th17-Mediated Stimulation of Dopamine Receptor D5 Expressed. J. Immunol. 188, 3062-3070 (2012)
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Role of dopamine in the physiology of T-cells and dendritic cells

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Dendritic cells (DCs) are responsible for priming T-cells and for promoting their differentiation from naïve T-cells into appropriate effector cells. Because of their fundamental roles in controlling immunity, DCs and T-cells require tight regulatory mechanisms. Several studies have shown that dopamine, not only mediate interactions into the nervous system, but can also contribute to the […]

Pacheco R., Prado C. E., Barrientos M. J., Bernales S. (2009). Role of dopamine in the physiology of T-cells and dendritic cells. Journal of Neuroimmunology, 216, 8-19.
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