Currently browsing: “2012”

Expression of Mitochondrial Non-coding RNAs (ncRNAs) Is Modulated by High Risk Human Papillomavirus (HPV) Oncogenes

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ABSTRACT Background: Antisense mitochondrial ncRNAs are down-regulated during oncogenesis by unknown mechanisms. Results: High risk HPV E2 oncogene induces down-regulation of the antisense transcripts. Additionally, E6 and E7 induce expression of a new sense mitochondrial ncRNA. Conclusion: HPV oncogenes modulate expression of mitochondrial ncRNAs. Significance: During non-viral oncogenesis, cellular factor(s), analogously to E2, could induce […]

Villota C, América Campos A, Soledad Vidaurre S, Oliveira-Cruz L, Boccardo E, Burzio V, Varas M, Villegas J, Villa L, Valenzuela PD, Socias M, Roberts S, Burzio L.O. Expression of Mitochondrial Non-coding RNAs (ncRNAs) Is Modulated by High Risk Human Papillomavirus (HPV) Oncogenes. The Journal of Biological Chemistry, vol. 287. 25, pp. 21303–21315. (2012)
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Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer

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ABSTRACT Background: Bladder cancer is a significant cause of morbidity and mortality with a high recurrence rate. Early detection of bladder cancer is essential in order to remove the tumor, to preserve the organ and to avoid metastasis. The aim of this study was to analyze the differential expression of mitochondrial non-coding RNAs (sense and […]

Rivas A, Burzio V, Landerer E, Borgna V, Gatica S, Ávila R, López C, Villota C, De la Fuente R, Echenique J, Burzio L.O.Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer. BMC Urology, 12:37 (2012)
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Immunity on Dendritic Cells Potentiates Th17-Mediated Stimulation of Dopamine Receptor D5 Expressed

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ABSTRACT: Dendritic cells (DCs) are responsible for priming T cells and for promoting their differentiation from naive T cells into appropriate effector cells. Emerging evidence suggests that neurotransmitters can modulate T cell-mediated immunity. However, the involvement of specific neurotransmitters or receptors remains poorly understood. In this study, we analyzed the role of dopamine in the regulation of DC […]

Prado C., Contreras F., González H., Díaz P., Elgueta D., Barrientos M., Herrada A. A., Lladser À., Bernales S. and Pacheco R. Immunity on Dendritic Cells Potentiates Th17-Mediated Stimulation of Dopamine Receptor D5 Expressed. J. Immunol. 188, 3062-3070 (2012)
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