Currently browsing: “2010”

Use of vectors expressing intracellular polynucleotide binding proteins as adjuvants

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Ljungberg K, Lladser A, Kiessling R. Use of vectors expressing intracellular polynucleotide binding proteins as adjuvants. International patent application No.: US2009/005753. International filing date: 22.10.2009. Publication No.: WO 2010/120271. Publication date: 21.10.2010

Ljungberg K, Lladser A, Kiessling R. Use of vectors expressing intracellular polynucleotide binding proteins as adjuvants. International patent application No.: US2009/005753. International filing date: 22.10.2009. Publication No.: WO 2010/120271. Publication date: 21.10.2010
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Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus

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ABSTRACT: Autoantibodies are of central importance in the pathogenesis of Ab-mediated autoimmune disorders. The murine lupus susceptibility locus Nba2 on chromosome 1 and the syntenic human locus are associated with a loss of immune tolerance that leads to antinuclear Ab production. To identify gene intervals within Nba2 that control the development of autoantibody-producing B cells […]

Jorgensen T. N., Alfaro J., Enriquez H. L., Jiang C., Loo W. M., Atencio S., Bupp M. R., Mailloux C. M., Metzger T., Flannery S., Rozzo S. J., Kotzin B. L., Rosemblatt M., Bono M. R. and Erickson L. D. Development of murine lupus involves the combined genetic contribution of the SLAM and FcyR intervals within the Nba2 autoimmune susceptibility locus. The J. Immunol. 15, 775-786 (2010)
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