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Role of CD26-adenosine deaminase interaction in the T cell-mediated immunity

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ABSTRACT: CD26 is a 110 kDa surface-bound ectopeptidase with intrinsic dipeptidyl peptidase IV (DPP IV) activity, which binds ade- nosine deaminase (ADA) on the surface of T cells. ADA is an enzyme of the purine metabolism that has been the object of consi- derable interest mainly because the congenital defect causes severe combined immunodeficiency (SCID). […]

Pacheco R., Lluis C., Franco R. (2005). Role of CD26-adenosine deaminase interaction in the T cell-mediated immunity. Inmunología, 24(2): 235-45.
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